The review deals with the properties of astacin family of zinc-dependent metalloproteinases. One of the remarkable features of these enzymes is their ability to cleave peptidyl-arylamides, which is not typical to other metalloproteinases. Special attention is paid to physiological functions of the astacins and to the influence of domain composition and posttranslational modifications on the activity and stability of these enzymes.
Stцcker W., Grams F., Baumann U., Reinemer P., Gomis-Rьth F.X., Mc Kay D.B., Bode W. (1995) Protein Sci., 4, 823-840. Scholar google search
Stцcker W. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1219-1222. Scholar google search
Borchert N., Becker-Pauly C., Wagner A., Fischer P., Stцcker W., Brattig N.W. (2007) Microbes Infect., 9, 498-506. Scholar google search
Rawlings N.D., Morton F.R., Kok C.Y., Kong J., Barrett A.J. (2008) Nucleic Acids Res., 36, D320-D325. Scholar google search
Bode W., Gomis-Rьth F.X., Huber R., Zwilling R., Stцcker W. (1992) Nature, 358, 164-167. Scholar google search
Garrigue-Antar L., Barker C., Kadler K.E. (2001) J. Biol. Chem., 276, 26237-26242. Scholar google search
Butler G.S., Tam E.M., Overall C.M. (2004) J. Biol. Chem., 279, 15615-15620. Scholar google search
Hege T., Baumann U. (2000) Acta Cryst. A, 56 (Supplement), s. 253. Scholar google search
Yokozawa Y., Tamai H., Tatewaki S., Tajima T., Tsuchiya T., Kanzawa N. (2002) J. Biochem., 132, 751-758. Scholar google search
Johnson G.D., Bond J.S. (1997) J. Biol. Chem., 272, 28126-28132. Scholar google search
Jiang W., Bond J.S. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1243-1245. Scholar google search
Mцhrlen F., Hutter H., Zwilling R. (2003) Eur. J. Biochem., 270, 4909-4920. Scholar google search
Porter S., Clark I.M., Kevorkian L., Edwards D.R. (2005) Biochem. J., 386, 15-27. Scholar google search
Quesada V., Sanchez L.M., Alvarez J., Lopez-Otin C. (2004) J. Biol. Chem., 279, 26627-26634. Scholar google search
Sarras M.P., Yan L., Leontovich A., Zhang J.S. (2002) Cell Res., 12, 163-176. Scholar google search
Mцhrlen F., Maniura M., Plickert G., Frohme M., Frank U. (2006) Evol. Dev., 8, 223-231. Scholar google search
Pan T., Groger H., Schmid V., Spring J. (1998) Dev. Genes Evol., 208, 259-266. Scholar google search
Xiong X., Chen L., Li Y., Xie L., Zhang R. (2006) Biochim. Biophys. Acta, 1759, 526-534. Scholar google search
Tsukuba T., Bond J.S. (1998) J. Biol. Chem., 273, 35260-35267. Scholar google search
Tang J., Bond J.S. (1998) Arch. Biochem. Biophys., 349, 192-200. Scholar google search
Hahn D., Lottaz D., Sterchi E.E. (1997) Eur. J. Biochem., 247, 933-941. Scholar google search
Litovchik L., Chestukhin A., Shaltiel S. (1998) J. Biol. Chem., 273, 29043-29051. Scholar google search
Hahn D., Pischitzis A., Rцsmann S., Hansen M.K., Leuenberger B., Luginbьhl U., Sterchi E.E. (2003) J. Biol. Chem., 278, 42829-42839. Scholar google search
Fan T.J., Katagiri C. (2001) Eur. J. Biochem., 268, 4892-4898. Scholar google search
Wermter C., Howel M., Hintze V., Bombosch B., Aufenvenne K., Yiallouros I., Stцcker W. (2007) Biol. Chem., 388, 513-521. Scholar google search
Garrigue-Antar L., Franзois V., Kadler K.E. (2004) J. Biol. Chem., 279, 49835-49841. Scholar google search
Hartigan N., Garrigue-Antar L., Kadler K.E. (2003) J. Biol. Chem., 278, 18045-18049. Scholar google search
Hung C.H., Huang H.R., Huang C.J., Huang F.L., Chang G.D. (1997) J. Biol. Chem., 272, 13772-13778. Scholar google search
Mцhrlen F., Baus S., Gruber A., Rackwitz H.-R., Schnolzer M., Vogt G., Zwilling R. (2001) Eur. J. Biochem., 268, 2540-2546. Scholar google search
Ravi Ram K., Sirot L.K., Wolfner M.F. (2006) Proc. Natl. Acad. Sci. USA., 103, 18674-18679. Scholar google search
Leighton M., Kadler K.E. (2003) J. Biol. Chem., 278, 18478-18484. Scholar google search
Yasumasu S., Yamagami K. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J Rawlings., N.D. and Woessner J.F.). Academic Press, London, pp. 1233-1235. Scholar google search
Yasumasu S., Yamagami K. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1235-1236. Scholar google search
Becker C., Kruse M.N., Slotty K.A., Kohler D., Harris J.R., Rцsmann S., Sterchi E.E., Stцcker W. (2003) Biol. Chem., 384, 825-831. Scholar google search
Johnson G.S., Bond J.S. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1227-1229. Scholar google search
Yiallouros I., Kappelhoff R., Schilling O., Wegmann F., Helms M.W., Auge A., Brachtendorf G., Berkhoff E.G., Beermann B., Hinz H.J., Konig S., Peter-Katalinic J., Stцcker W. (2002) J. Mol. Biol., 324, 237-246. Scholar google search
Lun H.M., Mak C.H., Ko R.C. (2003) Parasitol. Res., 90, 27-37. Scholar google search
Lhomond G., Ghiglione C., Lepage T., Gache C. (1996) Eur. J. Biochem., 238, 744-751. Scholar google search
Kawaguchi M., Yasumasu S., Hiroi J., Naruse K., Inoue M., Iuchi I. (2006) Dev. Genes Evol., 216, 769-784. Scholar google search
Yasumasu S., Shimada H., Inohaya K., Yamazaki K., Iuchi I., Yasumasu I., Yamagami K. (1996) Eur. J. Biochem., 237, 752-758. Scholar google search
Kessler E. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1236-1240. Scholar google search
Becker-Pauly C., Howel M., Walker T., Vlad A., Aufenvenne K., Oji V., Lottaz D., Sterchi E.E., Debela M., Magdolen V., Traupe H., Stцcker W. (2007) J. Invest. Dermatol., 127, 1115-1125. Scholar google search
Henning S.J., Oesterreicher T J., Osterholm D.E., Lottaz D., Hahn D., Sterchi E. (1999) FEBS Lett., 462, 368-372. Scholar google search
Johnson G.S., Bond J.S. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1222-1226. Scholar google search
Beynon R.J., Oliver S., Robertson D.H. (1996) Biochem. J., 315, 461-465. Scholar google search
Kadowaki T., Tsukuba T., Bertenshaw G.P., Bond J.S. (2000) J. Biol Chem., 275, 25577-25584. Scholar google search
Garrigue-Antar L., Hartigan N., Kadler K.E. (2002) J. Biol. Chem., 277, 43327-43334. Scholar google search
Leuenberger B., Hahn D., Pischitzis A., Hansen M.K., Sterchi E.E. (2003) Biochem. J., 369, 659-665. Scholar google search
Villa J.P., Bertenshaw G.P., Bylander J.E., Bond J.S. (2003) Biochem. Soc. Symp., 70, 53-63. Scholar google search
Ishmael F.T., Norcum M.T., Benkovic S.J., Bond J.S. (2001) J. Biol. Chem., 276, 23207-23211. Scholar google search
Bertenshaw G.P., Norcum M.T., Bond J.S. (2003) J. Biol. Chem., 278, 2522-2532. Scholar google search
Butler P.E, Bond J.S. (1988) J. Biol. Chem., 263, 13419-13426. Scholar google search
Foradori M.J., Tillinghast E.K., Smith J.S., Townley M.A., Mooney R.E. (2006) Comp. Biochem. Physiol. B Biochem. Mol. Biol., 143, 257-268. Scholar google search
McCall K.A., Huang C.C., Fierke C.A. (2000) J. Nutr., 130, 1437S-1446S. Scholar google search
da Silva G.F., Reuille R.L., Ming L.J., Livingston B.T. (2006) J. Biol. Chem., 281, 10737-10744. Scholar google search
Soler D., Nomizu T., Brown W.E., Shibata I., Auld D.S. (1995) J. Protein Chem., 14, 511-520. Scholar google search
Tarentino A.L. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1241-1242. Scholar google search
Ge G., Zhang Y., Steiglitz B.M., Greenspan D.S. (2006) J. Biol. Chem., 281, 10786-10798. Scholar google search
Sterchi E.E., Naim H.Y., Lentze M.J., Hauri H.P., Fransen J.A. (1988) Arch. Biochem. Biophys., 265, 105-118. Scholar google search
Sterchi E.E. (1998) in: Handbook of Proteolytic Enzymes (eds. Barrett A.J., Rawlings N.D. and Woessner J.F.). Academic Press, London, pp. 1229-1232. Scholar google search
Ge G., Seo N.S., Liang X., Hopkins D.R., Hook M., Greenspan D.S. (2004) J. Biol. Chem., 279, 41626-41633. Scholar google search
Stцcker W., Gomis-Rьth F.X., Bode W., Zwilling R. (1993) Eur. J. Biochem., 214, 215-231. Scholar google search
Wolz R.L., Harris R.B., Bond J.S. (1991) Biochemistry, 30, 8488-8493. Scholar google search
Yan L., Leontovich A., Fei K., Sarras M.P., Jr. (2000) Dev. Biol., 219, 115-128. Scholar google search
Kruse M.N., Becker C., Lottaz D., Kohler D., Yiallouros I., Krell H.W., Sterchi E.E., Stцcker W. (2004) Biochem. J., 378, 383-389. Scholar google search
da Silveira R.B., Wille A.C., Chaim O.M., Appel M.H., Silva D.T., Franco C.R., Toma L., Mangili O.C., Gremski W., Dietrich C.P., Nader H.B., Veiga S.S. (2007) Biochem. J., 406, 355-363. Scholar google search
Yasumasu S., Iuchi I., Yamagami K. (1989) J. Biochem. (Tokyo), 105, 212-218. Scholar google search
Kijimoto T., Watanabe M., Fujimura K., Nakazawa M., Murakami Y., Kuratani S, Kohara Y., Gojobori T., Okada N. (2005) Mol. Biol. Evol., 22, 1649-1660. Scholar google search
Lee S.T., Kessler E., Greenspan D.S. (1990) J. Biol. Chem., 265, 21992-21996. Scholar google search
Reynolds S.D., Zhang D., Puzas J.E., O`Keefe R.J., Rosier R.N., Reynolds P.R. (2000) Gene, 248, 233-243. Scholar google search
Richard-Blum S., Bernocco S., Font B., Moali C., Eichenberger D., Farjanel J., Burkhardt E.R., van der Rest M., Kessler E., Hulmes D.J.S. (2002) J. Biol. Chem., 277, 33864-33869. Scholar google search
Serpe M., Ralston A., Blair S.S., O`Connor M.B. (2005) Development, 132, 2645-2656. Scholar google search
Guncheva M., Dolashka-Angelova P., Stambolieva N. (2002) Biochim. Biophys. Acta, 1597, 335-338. Scholar google search
Stцcker W., Sauer B., Zwilling R. (1991) Biol. Chem. Hoppe Seyler, 372, 385-392. Scholar google search
Lottaz D., Buri C., Monteleone G., Rцsmann S., Macdonald T.T., Sanderson I.R., Sterchi E.E. (2007) Biol. Chem., 388, 337-341. Scholar google search
Zwilling R., Dцrsam H., Torff H.J., Rцdl J. (1981) FEBS Lett., 127, 75-78. Scholar google search
Grams F., Brandstetter H., D`Alт S., Geppert D., Krell H.-W., Leinert H., Livi V., Menta E., Oliva A., Zimmermann G. (2001) Biol. Chem., 382, 1277-1285. Scholar google search
Delaet N.G., Robinson L.A., Wilson D.M., Sullivan R.W., Bradley E.K., Dankwardt S.M., Martin R.L., Van Wart H.E., Walker K.A. (2003) Bioorg. Med. Chem. Lett., 13, 2101-2104. Scholar google search
Baker A.H., Edwards D.R., Murphy G. (2002) J. Cell. Sci., 115, 3719-3727. Scholar google search
Lee H.X., Ambrosio A.L., Reversade B., De Robertis E.M. (2006) Cell, 124, 147-159. Scholar google search
Tsai P.L., Chen C.H., Huang C.J., Chou C.M., Chang G.D. (2004) J. Biol. Chem., 279, 11146-11155. Scholar google search
Hirano M., Ma B.Y., Kawasaki N., Okimura K., Baba M., Nakagawa T., Miwa K., Kawasaki N., Oka S., Kawasaki T. (2005) J. Immunol., 175, 3177-3185. Scholar google search
Yan J., Cheng Q., Li C.-B., Aksoy S. (2002) Insect Mol. Biol., 11, 57-65. Scholar google search
Ferreira A.H., Cristofoletti P.T., Lorenzini D.M., Guerra L.O., Paiva P.B., Briones M.R., Terra W.R., Ferreira C. (2007) J. Insect. Physiol., 53, 1112-1124. Scholar google search
Pappano W.N., Steiglitz B.M., Scott I.C., Keene D.R., Greenspan D.S. (2003) Mol. Cell. Biol., 23, 4428-4438. Scholar google search
Wayne Davis M., Birnie A.J., Chan A.C., Page A.P., Jorgensen E.M. (2004) Development, 131, 6001-6008. Scholar google search
Kessler E., Fichard A., Chanut-Delalande H., Brusel M., Ruggiero F. (2001) J. Biol. Chem., 276, 27051-27057. Scholar google search
Rattenholl A., Pappano W.N., Koch M., Keene D.R., Kadler K.E., Sasaki T., Timpl R., Burgeson R.E., Greenspan D.S., Bruckner-Tuderman L. (2001) J. Biol. Chem., 277, 26372-26378. Scholar google search
Steiglitz B.M., Ayala M., Narayanan K., George A., Greenspan D.S. (2004) J. Biol. Chem., 279, 980-986. Scholar google search
Scott I.C., Imamura Y., Pappano W.N., Troedel J.M., Recklies A.D., Roughley P.J., Greenspan D.S. (2000) J. Biol. Chem., 275, 30504-30511. Scholar google search
Hasilik A. (2007) in: Biochemie und Pathobiochemie (Georg Lцffler, Petro E. Petrides and Peter C. Heinrich, eds), Springer, Berlin-Heidelberg, pp. 317-318. Scholar google search
Borel A., Eichenberger D., Farjanel J., Kessler E., Gleyzal S., Hulmes D.J., Sommer P., Font B. (2001) J. Biol. Chem., 276, 48988-48989. Scholar google search
Crisman J.M., Zhang B., Norman L.P., Bond J.S. (2004) J. Immunol., 172,4510-4519. Scholar google search
Lottaz D., Maurer C.A., Hahn D., Bьchler M.W., Sterchi E.E. (1999) Cancer Res., 59, 1127-1133. Scholar google search
Padanilam B.J. (2003) Am. J. Physiol. Renal. Physiol., 284, F608-F627. Scholar google search
Schьtte A., Lottaz D., Sterchi E.E., Stцcker W., Becker-Pauly C. (2007) Biol. Chem., 388, 523-531. Scholar google search
Herzog C., Seth R., Shah S.V., Kaushal G.P. (2007) Kidney Int., 71, 1009-1018. Scholar google search
Rцsmann S., Hahn D., Lottaz D., Kruse M.N., Stцcker W., Sterchi E.E. (2002) J. Biol. Chem., 277, 40650-40658. Scholar google search
Ha T.-S., Barnes J.L, Stewart J.L., Ko W.C., Miner J.H, Abrahamson D.R., Sanes J.R., Kasinath B.S. (1999) J. Am. Soc. Nephrol., 10, 1931-1939. Scholar google search
Shibata I., Iwamatsu T., Oba Y., Kobayashi D., Tanaka M., Nagahama Y., Suzuki N., Yoshikuni M. (2000) J. Biol. Chem., 275, 8349-8354. Scholar google search
Song H.D., Sun X.J., Deng M., Zhang G.W., Zhou Y., Wu X.Y., Sheng Y., Chen Y., Ruan Z., Jiang C.L., Fan H.Y., Zon L.I., Kanki J.P., Liu T.X., Look A.T., Chen Z. (2004) Proc. Natl. Acad. Sci USA, 101, 16240-16245. Scholar google search