The astacin family of metalloproteinases

   
Semenova S.A.1 , Rudenskaya G.N.1

1. School of Chemistry, Moscow State University
Section: Review
UDK: 577.152.3      PubMed Id: 19105396
Year: 2008  Volume: 54  Issue: 5  Pages: 531-554
The review deals with the properties of astacin family of zinc-dependent metalloproteinases. One of the remarkable features of these enzymes is their ability to cleave peptidyl-arylamides, which is not typical to other metalloproteinases. Special attention is paid to physiological functions of the astacins and to the influence of domain composition and posttranslational modifications on the activity and stability of these enzymes.
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Semenova S.A., Rudenskaya G.N. (2008) Biomeditsinskaya khimiya, 54(5), 531-554.
This paper is also available as the English translation:10.1134/S199075080901003X
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