Reduced glutathione interaction with thiophosphoric derivatives of alkaloids of Chelidonium majus L. in vitro

   
Glazev A.1, Nefyodov L.1

1. Laboratory of Biochemistry of Biologically Active Substances Yanka Kupala State University of Grodno
Section: Experimental/Clinical Study
UDK: 547.915+547.94+535.37      PubMed Id: 19351041
Year: 2009  Volume: 55  Issue: 1  Pages: 114-120
The interaction between reduced glutathione and thiophosphoric derivatives of alkaloids of greater celandine was studied by the photometric method of analysis and fluorescence spectroscopy in vitro. Results demonstrate possibility of specific interaction between reduced glutathione and thiophosphoric derivatives of alkaloids. It is possible that similar interaction of thiophosphoric derivatives of alkaloids may involve SH-groups of amino-acid residues, at the active sites of some metabolic enzymes.
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Glazev A., Nefyodov L. (2009) Biomeditsinskaya khimiya, 55(1), 114-120.
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