The textile materials containing chitosan and proteolytic complex from hepatopancreas of the crab, for the medical purposes

   
Belov A.A.1 , Belova E.N.1, Filatov V.N.1

1. Research Institute of Textile Materials, Moscow, Mendeleyev Russian University of Chemical Engineering
Section: Experimental/Clinical Study
PubMed Id: 19351034
Year: 2009  Volume: 55  Issue: 1  Pages: 61-67
Positively charged carriers were synthesized on the basis of the cellulose, oxidized cellulose and chitosan; they were used for immobilization of the proteolytic complex from crab hepatopancreas (CHP). Optimum conditions, a method of updating and a degree of updating of the textile carrier for immobilizations at which practically does not occur inactivation the CHP in process immobilizations were found. Under optimal conditions inactivation kinetics during storage of CHP immobilized on the textile carriers was similar to the inactivation kinetics of immobilized pancreatic trypsin.Experiments on rats have shown, that employment of a new material accelerated wound healing process.
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Keywords: immobilization, chitosan, proteolytices enzymes, collagenase, inactivation, purulent wounds
Citation:

Belov, A. A., Belova, E. N., Filatov, V. N. (2009). The textile materials containing chitosan and proteolytic complex from hepatopancreas of the crab, for the medical purposes. Biomeditsinskaya khimiya, 55(1), 61-67.
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