Samples of human blood plasma were irradiated with the laser beam (λ=633 nm, P=13 mW, t=20 min) in vitro. In experimental and control (incubated in the dark) samples the complement hemolytic activity was measured. Laser irradiation had minor influence on the duration of lag-period and the rate of complement-dependent hemolysis via classical and alternative pathways; it also did not alter the functional activity of factor B, components C2 and C3. Nevertheless laser irradiation effect was seen in essential reduction of a bystander lysis coefficient. This new fact can elucidate some aspects of the clinical effectiveness of the blood laser irradiation.
Galebskaya L.V., Andreeva L.A., Solovtsova I.L., Petrishchev N.N., Solov'eva M.A. (2009) The stydy of the human complement cascade of proteolysis as a target of laser irradiation. Biomeditsinskaya Khimiya, 55(1), 68-72.
Galebskaya L.V. et al. The stydy of the human complement cascade of proteolysis as a target of laser irradiation // Biomeditsinskaya Khimiya. - 2009. - V. 55. -N 1. - P. 68-72.
Galebskaya L.V. et al., "The stydy of the human complement cascade of proteolysis as a target of laser irradiation." Biomeditsinskaya Khimiya 55.1 (2009): 68-72.
Galebskaya, L. V., Andreeva, L. A., Solovtsova, I. L., Petrishchev, N. N., Solov'eva, M. A. (2009). The stydy of the human complement cascade of proteolysis as a target of laser irradiation. Biomeditsinskaya Khimiya, 55(1), 68-72.
