Metabolic fingerprinting of blood plasma for patients with prostate cancer

   
Lokhov P.G.1 , Dashtiev M.I.1, Bondartsсov L.V.1, Lisitsa А.V.1, Moshkovskii S.A.1, Archakov A.I.1

1. Institute of Biomedical Chemistry RAMS
Section: Experimental/Clinical Study
UDK: 543.51.061:543.54.45:543.8      PubMed Id: 19663000
Year: 2009  Volume: 55  Issue: 3  Pages: 247-254
Application of blood plasma metabolites fingerprinting for the diagnostic of the 2nd stage of prostate cancer has been investigated. The diagnostic sensitivity (95%), specificity (96,7%) and accuracy (95,7%) of the metabolic fingerprinting were much higher then those for PSA test (35%, 83,3% and 51,7%, respectively) for the same patients. Area under the ROC-curve (0,994) suggests that the proposed approach is effective and can be used for clinical applications.
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Lokhov P.G., Dashtiev M.I., Bondartsсov L.V., Lisitsa А.V., Moshkovskii S.A., Archakov A.I. (2009) Biomeditsinskaya khimiya, 55(3), 247-254.
This paper is also available as the English translation:10.1134/S1990750810010051
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