Stress and thyroid gland

Nadolnik L.I.1

1. Institute Pharmacology of Biochemistry National Academy of Sciences of Belarus
Section: Review
DOI: 10.18097/pbmc20105604443      PubMed Id: 21032895
Year: 2010  Volume: 56  Issue: 4  Pages: 443-456
The review highlights the effects of acute and chronic stress on thyroid metabolism. Special attention is paid to the influence of stress and the direct effects of glucocorticoids on the thyroid status, the activities of thyrocyte iodine uptake, oxidation and organification as well as peripheral metabolism of thyroid hormones (deposition and transport of thyroid hormones, deiodinase activities in different tissues). The role of stress in the development of thyroid pathology is analysed and charestiristic features of thyroid function alterations during impaired functioning of the pitiutary-adrenal system are established. The mechanisms of the stress-induced impairments in thyroid functions are of interest for further research, taking into consideration serious consequences of thyroid deficiency for the body, even in subclinical thyroid insufficiency.
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Keywords: stress, glucocorticoids, thyroid, iodine absorption and organification, deiodinases, stress-induced thyroid pathology

Nadolnik, L. I. (2010). Stress and thyroid gland. Biomeditsinskaya khimiya, 56(4), 443-456.
This paper is also available as the English translation: 10.1134/S1990750811020119
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