HIV infection is accompanied by activation of lipid peroxidation, oxidative modification of lipoprotein complexes, and a decrease in activity of antioxidant enzymes (superoxide dismutase (SOD), catalase and glutathione peroxidase (GP)) in blood serum. A significant increase of glutathione reductase observed under these conditions is considered as a function of the antioxidant defence. These changes were already seen at early (symptomless) stages of this disease, however, at manifested forms they were more pronounced.
Download PDF:
Keywords: pro- and antioxidants, oxidative stress, HIV, AIDS
Citation:
Kostyushov V.V., Bokal I.I., Petrov S.A. (2010) Study of activity of enzymes of antioxidant system of blood at HIV infection. Biomeditsinskaya Khimiya, 56(5), 596-601.
Kostyushov V.V. et al. Study of activity of enzymes of antioxidant system of blood at HIV infection // Biomeditsinskaya Khimiya. - 2010. - V. 56. -N 5. - P. 596-601.
Kostyushov V.V. et al., "Study of activity of enzymes of antioxidant system of blood at HIV infection." Biomeditsinskaya Khimiya 56.5 (2010): 596-601.
Kostyushov, V. V., Bokal, I. I., Petrov, S. A. (2010). Study of activity of enzymes of antioxidant system of blood at HIV infection. Biomeditsinskaya Khimiya, 56(5), 596-601.