Study of activity of enzymes of antioxidant system of blood at HIV infection

   
Kostyushov V.V.1 , Bokal I.I.2, Petrov S.A.2

1. Military medical clinical center of South region
2. Mechnikov Odessa National University
Section: Experimental/Clinical Study
DOI: 10.18097/pbmc20105605596      PubMed Id: 21254630
Year: 2010  Volume: 56  Issue: 5  Pages: 596-601
HIV infection is accompanied by activation of lipid peroxidation, oxidative modification of lipoprotein complexes, and a decrease in activity of antioxidant enzymes (superoxide dismutase (SOD), catalase and glutathione peroxidase (GP)) in blood serum. A significant increase of glutathione reductase observed under these conditions is considered as a function of the antioxidant defence. These changes were already seen at early (symptomless) stages of this disease, however, at manifested forms they were more pronounced.
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Keywords: pro- and antioxidants, oxidative stress, HIV, AIDS
Citation:

Kostyushov, V. V., Bokal, I. I., Petrov, S. A. (2010). Study of activity of enzymes of antioxidant system of blood at HIV infection. Biomeditsinskaya khimiya, 56(5), 596-601.
This paper is also available as the English translation: 10.1134/S1990750811020041
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