1. Moscow Scientific Research Institute of Medical Ecology
M.V. Lomonosov Moscow State Academy of Fine Chemical Technology 2. Moscow Scientific Research Institute of Medical Ecology
I.M. Sechenov Moscow Medical Academy 3. Moscow Scientific Research Institute of Medical Ecology 4. I.M. Sechenov Moscow Medical Academy 5. M.V. Lomonosov Moscow State Academy of Fine Chemical Technology
Telomerase activity (TA) was examined in gastric adenocarcinomas and gastric lymphoma using a modified TRAP assay. TA was present in 16 of 18 (89%) gastric adenocarcinomas and in gastric lymphoma, whereas no TA was detected in normal tissue. Almost all samples had "high" and "very high" TA levels. Telomerase is undoubtedly associated with the process of malignant transformation and therefore can be an important marker for diagnostics of gastric cancer.
Svinareva L.V. et al. Detection of telomerase activity in gastric cancer // Biomeditsinskaya Khimiya. - 2010. - V. 56. -N 5. - P. 602-608.
Svinareva L.V. et al., "Detection of telomerase activity in gastric cancer." Biomeditsinskaya Khimiya 56.5 (2010): 602-608.
Svinareva, L. V., Glukhov, A. I., Zimnik, O. V., Bykov, I. I., Khorobrykh, T. V., Shvets, V. I. (2010). Detection of telomerase activity in gastric cancer. Biomeditsinskaya Khimiya, 56(5), 602-608.