Synthetic peptide vaccines

   
Moysa A.A.1 , Kolesanova E.F.1

1. Institute of Biomedical Chemistry, Russian Academy of Medical sciences
Section: Review
DOI: 10.18097/PBMC20115701014      PubMed Id: 21516776
Year: 2011  Volume: 57  Issue: 1  Pages: 14-30
This review considers the stages of the development of synthetic peptide vaccines against infectious agents, novel approaches and technologies employed in this process, including bioinformatics, genomics, proteomics, large-scale peptide synthesis, high-throughput screening methods, the use of transgenic animals for modelling human infections. An important role for the development and selection of efficient adjuvants for peptide immunogens is noted. Examples of synthetic peptide vaccine developments against three infectious diseases (malaria, hepatitis C, and foot-and-mouth disease) are given.
Download PDF:  
Keywords: vaccine, peptides, B-epitopes, T-epitopes, immune response, malaria, hepatitis C virus
Citation:

Moysa, A. A., Kolesanova, E. F. (2011). Synthetic peptide vaccines. Biomeditsinskaya Khimiya, 57(1), 14-30.
This paper is also available as the English translation: 10.1134/S1990750810040025
References
 2026 (vol 72)
 2025 (vol 71)
 2024 (vol 70)
 2023 (vol 69)
 2022 (vol 68)
 2021 (vol 67)
 2020 (vol 66)
 2019 (vol 65)
 2018 (vol 64)
 2017 (vol 63)
 2016 (vol 62)
 2015 (vol 61)
 2014 (vol 60)
 2013 (vol 59)
 2012 (vol 58)
 2011 (vol 57)
 2010 (vol 56)
 2009 (vol 55)
 2008 (vol 54)
 2007 (vol 53)
 2006 (vol 52)
 2005 (vol 51)
 2004 (vol 50)
 2003 (vol 49)
◄        ►