1. Department of Chemical Technology of Biologically Active Compounds, M.V. Lomonosov Moscow Academy of Fine Chemical Technology 2. Blokhin Oncological Research Center, Russian Academy of Medical Sciences
Mutagenic activity of non-phosphorous cationic alkyl glycerolipid rac-N-{ 4-[(2-Methoxy- 3-octadecyloxy)propyl]oxycarbonylbutyl}-N,N-dimethyl-N-(2-hydroxyethyl) ammonium iodide was evaluated. According performed Ames assay results indicated on non-mutagenic properties tested compound. Resulting data open the possibility to carry out biological study in vivo for class of ether cationic glycerolipids and further applications as a potential agent of anticancer therapy.
Romanova S.G., Belickii G.A., Hitrovo I.A., Serebrennikova G.A., Shtil A.A. (2011) Studies of mutagenic activity of positively charged alkyl glycerolipids in ames test. Biomeditsinskaya Khimiya, 57(4), 429-434.
Romanova S.G. et al. Studies of mutagenic activity of positively charged alkyl glycerolipids in ames test // Biomeditsinskaya Khimiya. - 2011. - V. 57. -N 4. - P. 429-434.
Romanova S.G. et al., "Studies of mutagenic activity of positively charged alkyl glycerolipids in ames test." Biomeditsinskaya Khimiya 57.4 (2011): 429-434.
Romanova, S. G., Belickii, G. A., Hitrovo, I. A., Serebrennikova, G. A., Shtil, A. A. (2011). Studies of mutagenic activity of positively charged alkyl glycerolipids in ames test. Biomeditsinskaya Khimiya, 57(4), 429-434.
References
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