Effect of water on silica gel adsorption with respect to human blood plasma components

   
Gal L.N.1, Malachova M.Ya.2, Melenevskaya E.Yu.3 , Podosenova N.G.1, Sharonova L.V.4

1. Institute for Analytic Instrumentation, RAS
2. Medical Academy of postgraduate education
3. Institute of Macromolecular Compounds, RAS
4. Ioffe Physico-Technical Institute, RAS
Section: Experimental/Clinical Study
DOI: 10.18097/pbmc20115706635      PubMed Id: 22359919
Year: 2011  Volume: 57  Issue: 6  Pages: 635-641
In this work, the study of properties of silica gel as an adsorbent for plasmasorption has been performed. Investigations have been realized of the effect of silica gel preliminary treatment conditions and a period of plasma with silica gel contact on plasmasorption characteristics of human blood plasma components, such as protein, triglycerides, cholesterol (high-density and low-density one). The results obtained can be used for variation of silica gel adsorption properties, in situ at the adsorbent preparation process. For explanation of the experimental concentration and kinetic (temporal) characteristics of plasmasorption, the model of silica gel grains charging at the hydration was used.
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Keywords: adsorption, desorption, silica gel, hydration, human blood plasma components, cholesterol
Citation:

Gal, L. N., Malachova, M. Ya., Melenevskaya, E. Yu., Podosenova, N. G., Sharonova, L. V. (2011). Effect of water on silica gel adsorption with respect to human blood plasma components. Biomeditsinskaya khimiya, 57(6), 635-641.
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