Lipid-proteinic interaction in erythrocytie and placental membranes in women with insulin resistance

   
Mikaelyan N.P.1 , Terentyev A.A.1, Maxina A.G.1, Mikaelyan A.V.2, Novikova S.V.2

1. Russian State Medical University
2. Moscow Regional Research Institute for Obstetrics and Ginecology
Section: Experimental/Clinical Study
DOI: 10.18097/pbmc20125802224      UDK: 577.169:618.36 + 577.15: 577.17+577.164.1      PubMed Id: 22724362
Year: 2012  Volume: 58  Issue: 2  Pages: 224-229
Disturbances of erythrocyte and placental membrane functiond have been studied in placenta of pregnant women with obesity and diabetes mellitus type 2. The results of this study demonstrate significant metabolic impairments in women with insulin resistance. Changes in lipid spectrum of erythrocyte membranes and decreased activity of antioxidant enzymes obviously contribute to the development of fetoplacental insufficiency. This changes point to necessity of the antioxidant therapy in pregnant women with obesity and diabetes mellitus type 2.
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Mikaelyan N.P., Terentyev A.A., Maxina A.G., Mikaelyan A.V., Novikova S.V. (2012) Biomeditsinskaya khimiya, 58(2), 224-229.
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