The knee joint osteoarthrosis is accompanied by activation of the oxidative stress in the synovial liquid. Specific treatment decreased or even normalized such biochemical parameters of the synovial liquid as the carbonyl groups, thiobarbituric acid reactive substances (TBARS) and total protein content. The most demonstrative changes were found for early and late markers of the oxidative modification of proteins. These parameters may be used in laboratory diagnostics of the depth of the degenerative-dystrophic process in the knee joint and for the estimation of the effectiveness of the treatment.
Meshcheryakova M.G., Trilis Ya.G., Kirillova N.V., Alpatova A.T., Muhin I.A., Kozhevin A.A. (2012) Some biochemical parameters of the synovial liquid for estimation of effectiveness of the treatment of the knee joint osteoarthrosis. Biomeditsinskaya Khimiya, 58(2), 230-236.
Meshcheryakova M.G. et al. Some biochemical parameters of the synovial liquid for estimation of effectiveness of the treatment of the knee joint osteoarthrosis // Biomeditsinskaya Khimiya. - 2012. - V. 58. -N 2. - P. 230-236.
Meshcheryakova M.G. et al., "Some biochemical parameters of the synovial liquid for estimation of effectiveness of the treatment of the knee joint osteoarthrosis." Biomeditsinskaya Khimiya 58.2 (2012): 230-236.
Meshcheryakova, M. G., Trilis, Ya. G., Kirillova, N. V., Alpatova, A. T., Muhin, I. A., Kozhevin, A. A. (2012). Some biochemical parameters of the synovial liquid for estimation of effectiveness of the treatment of the knee joint osteoarthrosis. Biomeditsinskaya Khimiya, 58(2), 230-236.
Alekseeva L.I. (2003) Nauchno-prakticheskaya revmatologiya, 5, 20-24. Scholar google search
Aldebel M.M. (2000) Biokhimicheskie pokazateli krovi, pochek krys s ehksperimental'nym khronicheskim glomerulonefritom. Diss. dokt. nauk, Spb. Scholar google search
Meshheryakova M.G., Alpatova T.F., Trilis YA.G., Mukhin I.A., Kirillova N.V. (2009) Sbornik nauchnykh trudov: Razrabotka, issledovanie i marketing novoj farmatsevticheskoj produktsii, Vyp. 64.- Pyatigorsk, s. 468-471. Scholar google search
Matveeva E.L. (2007) Biokhimicheskie izmeneniya v sinovial'noj zhidkosti pri razvitii degenerativno-distroficheskikh protsessov v kolennom sustave. Diss. dokt. nauk, Rossijskij nauchnyj tsentr "Vosstanovitel'naya travmatologiya i ortopediya" im. Akad. G.A. Ilizarova Roszdrava, Tyumen'. Scholar google search
Korzh L.A., CHernykh V.P., Filippenko V.A. (1997) Diagnostika i konservativnoe lechenie zabolevanij i povrezhdenij oporno-dvigatel'noj sistemy: Sprav.: V 8 kn. Kn. 2. Osteoartroz, Osnova, KHar'kov. Scholar google search
