Some biochemical parameters of the synovial liquid for estimation of effectiveness of the treatment of the knee joint osteoarthrosis

   
Meshcheryakova M.G.1 , Trilis Ya.G.1, Kirillova N.V.1, Alpatova A.T.1, Muhin I.A.2, Kozhevin A.A.2

1. Saint-Petersburg State Chemical-Pharmaceutical Academy, Federal Agency for Public Health and Social Development
2. Heriatric ortopedical hospital
Section: Experimental/Clinical Study
DOI: 10.18097/pbmc20125802230      UDK: 577.15:616.72.002      PubMed Id: 22724363
Year: 2012  Volume: 58  Issue: 2  Pages: 230-236
The knee joint osteoarthrosis is accompanied by activation of the oxidative stress in the synovial liquid. Specific treatment decreased or even normalized such biochemical parameters of the synovial liquid as the carbonyl groups, thiobarbituric acid reactive substances (TBARS) and total protein content. The most demonstrative changes were found for early and late markers of the oxidative modification of proteins. These parameters may be used in laboratory diagnostics of the depth of the degenerative-dystrophic process in the knee joint and for the estimation of the effectiveness of the treatment.
Download PDF:
Reference:

Meshcheryakova M.G., Trilis Ya.G., Kirillova N.V., Alpatova A.T., Muhin I.A., Kozhevin A.A. (2012) Biomeditsinskaya khimiya, 58(2), 230-236.
References  
 2019 (vol 65)
 2018 (vol 64)
 2017 (vol 63)
 2016 (vol 62)
 2015 (vol 61)
 2014 (vol 60)
 2013 (vol 59)
 2012 (vol 58)
 2011 (vol 57)
 2010 (vol 56)
 2009 (vol 55)
 2008 (vol 54)
 2007 (vol 53)
 2006 (vol 52)
 2005 (vol 51)
 2004 (vol 50)
 2003 (vol 49)
        

© Institute of Biomedical Chemistry, Moscow, Russia