The study of structural changes in influenza virus hemagglutinin (ha) after interaction with liposomes by the fluorescence method

   
Pogarskaya I.V.1, Kontarov N.A.1 , Balaev N.V.1, Yuminova N.V.1

1. Mechnikov Research Institute of Vaccines and Sera, Russian Academy of Medical Sciences
Section: Short Communication
DOI: 10.18097/pbmc20125802237      UDK: 577.152.3      PubMed Id: 22724364
Year: 2012  Volume: 58  Issue: 2  Pages: 237-240
Using the method of self fluorescence quenching influence of phospholipids on conformational state of HA has been studied. Interactions of HA with model phospholipids membranes are accompanied by changes of structure-dynamic protein organization. This method could be used for controlling the structure organization of proteins after receiving by virus the influenzal virusomal vaccine.
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Pogarskaya I.V., Kontarov N.A., Balaev N.V., Yuminova N.V. (2012) Biomeditsinskaya khimiya, 58(2), 237-240.
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