1. Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of Russian Academy of Science (FEB RAS) 2. Far East Federal University 3. Institute of Chemistry, FEB RAS
Pharmacological activity of echinochrome A (EchA) alone and in the biologically active additives (BAA) "Timarin", administered per os has been investigated on volunteers. EchA decreased serum glutatione (GSH) and increased catalase activity 1 h after treatment; catalase activity normalized, while GSH exceeded the initial level 3 h after the treatment. Changes in serum lipid spectrum, demonstrating reduction of the risk atherogenesis were determined.
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Keywords: echinochrome A, 1,4-naphtoquinone, pharmacological activity, mechanism action
Citation:
Artyukov A.A., Popov A.M., Tsybulsky A.V., Krivoshapko O.N., Polyakova N.V. (2012) Pharmacological activity echinochrome a singly and consisting of baa "timarin". Biomeditsinskaya Khimiya, 58(3), 281-290.
Artyukov A.A. et al. Pharmacological activity echinochrome a singly and consisting of baa "timarin" // Biomeditsinskaya Khimiya. - 2012. - V. 58. -N 3. - P. 281-290.
Artyukov A.A. et al., "Pharmacological activity echinochrome a singly and consisting of baa "timarin"." Biomeditsinskaya Khimiya 58.3 (2012): 281-290.
Artyukov, A. A., Popov, A. M., Tsybulsky, A. V., Krivoshapko, O. N., Polyakova, N. V. (2012). Pharmacological activity echinochrome a singly and consisting of baa "timarin". Biomeditsinskaya Khimiya, 58(3), 281-290.
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