Activities of enzymes involved in redox transformation of endogenous aldehydes have been investigated in subcellular fractions of liver, heart, and brain of pubertal rats exposed to prolonged immobilization stress. In the liver aldo-keto reductase (AKR) activity in the postmitochondrial fraction and aldehyde dehydrogenase (ALDH) acivity of the mitochondrial fraction demonstrated a more pronounced decrease in 2-month-old rats. Rat heart postmitochondrial AKR and ALDH demonstrated opposite changes in their enzymatic activities, while activity of mitochondrial ALDH remained unchanged. Brain cells create conditions that favor effective utilization of endogenous aldehydes in metabolic redox pathways.
Sukhova L.L., Guryeva A.V., Berezhnaya E.A., Davydov V.V. (2012) Activity of endogenous aldehydes catabolism enzymes in subcellular fractions of liver, heart and brain of rats at pubertal age under stress. Biomeditsinskaya Khimiya, 58(6), 691-701.
Sukhova L.L. et al. Activity of endogenous aldehydes catabolism enzymes in subcellular fractions of liver, heart and brain of rats at pubertal age under stress // Biomeditsinskaya Khimiya. - 2012. - V. 58. -N 6. - P. 691-701.
Sukhova L.L. et al., "Activity of endogenous aldehydes catabolism enzymes in subcellular fractions of liver, heart and brain of rats at pubertal age under stress." Biomeditsinskaya Khimiya 58.6 (2012): 691-701.
Sukhova, L. L., Guryeva, A. V., Berezhnaya, E. A., Davydov, V. V. (2012). Activity of endogenous aldehydes catabolism enzymes in subcellular fractions of liver, heart and brain of rats at pubertal age under stress. Biomeditsinskaya Khimiya, 58(6), 691-701.
Korenev N.M. (2001) Prognozuvannya ta profilaktika arterialnoyi gipertenzii v dityachomu ta pidlitkovomu vitsi: materiali simp., Harkov, 3-7 Scholar google search
Korenev M.M. Nosova O.M. (2002) Pediatria, akusherstvo ta ginekologiya, 2, 15-18. Scholar google search
Meerson F.Z. (1984) Patogenez i preduprezhdenie stressornyih i ishemicheskih povrezhdeniy serdtsa, Meditsina M., 270. Scholar google search
Giallauria F., Battimiello V., Veneziano M., De Luca P. (2007) Monaldi Arch. Chest Dis., 68(2), 74-80. Scholar google search
Rozanski A., Blumenthal J.A., Kaplan J. (1999) Circulation, 99(16), 2192-2217. Scholar google search
Galvez A.S., Ulloa J.A., Chiong M., Criollo A., Eisner V., Barros L.F., Lavandero S. (2003) J. Biol. Chem., 278(40), 38484-38494. CrossRef Scholar google search
Lowry O.H., Rosebrough K.J., Farr A.L., Randall K.I. (1951) J. Biol. Chem., 193(1), 265-275. Scholar google search
Gueraud F., Alary J., Costet P. (1999) J. Lipid. Res., 40, 152-159. Scholar google search
