The effects of repetitive mild hypobaric hypoxic preconditioning upon pro- and antioxidant systems in rat hippocampus were studied. It was found that three-trial preconditioning by mild hypobaric hypoxia (360 mm Hg, 2 h) induced moderate oxidative stress immediately after the last preconditioning trial. In addition, it down-regualted the levels of peptide antioxidants (Trx-1, Trx-2, Cu,Zn-SOD) and several lipid peroxidation products 24 h later.
Kislin M.S., Stroev S.A., Gluschenko T.S., Tulkova E.I., Pelto-Huikko M., Samoilov M.O. (2013) Hypoxic preconditioning modifies the activity of prond antioxidant systems in rat hippocampus. Biomeditsinskaya Khimiya, 59(6), 673-681.
Kislin M.S. et al. Hypoxic preconditioning modifies the activity of prond antioxidant systems in rat hippocampus // Biomeditsinskaya Khimiya. - 2013. - V. 59. -N 6. - P. 673-681.
Kislin M.S. et al., "Hypoxic preconditioning modifies the activity of prond antioxidant systems in rat hippocampus." Biomeditsinskaya Khimiya 59.6 (2013): 673-681.
Kislin, M. S., Stroev, S. A., Gluschenko, T. S., Tulkova, E. I., Pelto-Huikko, M., Samoilov, M. O. (2013). Hypoxic preconditioning modifies the activity of prond antioxidant systems in rat hippocampus. Biomeditsinskaya Khimiya, 59(6), 673-681.
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