Some peculiarities in the manifestation of oxidative stress and current status of antioxidant system in adolescents of different age groups with obesity, complicated by insulin resistance and without it
Kulieshova D.K.1 , Davydov V.V.1
1. Institute of Children and Adolescents Health Care of NAMS of Ukraine
The study has shown that neuroendocrine obesity in adolescents is associated with the formation of oxidative stress which is more pronounced in early than in late puberty. Obesity with concomitant insulin resistance increases manifestations of oxidative stress accompanied by a compensatory increase in the activity of catabolic enzymes and reduced capacity of the defense antioxidant system in late puberty. These alterations may be caused by age-related changes in hormonal secretion under conditions of insulin resistance in late puberty.
Kulieshova D.K., Davydov V.V. (2014) Some peculiarities in the manifestation of oxidative stress and current status of antioxidant system in adolescents of different age groups with obesity, complicated by insulin resistance and without it. Biomeditsinskaya Khimiya, 60(2), 264-274.
Kulieshova D.K. et al. Some peculiarities in the manifestation of oxidative stress and current status of antioxidant system in adolescents of different age groups with obesity, complicated by insulin resistance and without it // Biomeditsinskaya Khimiya. - 2014. - V. 60. -N 2. - P. 264-274.
Kulieshova D.K. et al., "Some peculiarities in the manifestation of oxidative stress and current status of antioxidant system in adolescents of different age groups with obesity, complicated by insulin resistance and without it." Biomeditsinskaya Khimiya 60.2 (2014): 264-274.
Kulieshova, D. K., Davydov, V. V. (2014). Some peculiarities in the manifestation of oxidative stress and current status of antioxidant system in adolescents of different age groups with obesity, complicated by insulin resistance and without it. Biomeditsinskaya Khimiya, 60(2), 264-274.
Rice-Evans C.A., Diplock A.T., Symons M.C.R. (1991) Laboratory techniques in biochemistry and molecular biology: techniques in free radical research, 291. Scholar google search
Kostiuk V.A., Potapovich A.I., Kovaleva Zh.V., A simple and sensitive method of determination of superoxide dismutase activity based on the reaction of quercetin oxidation, Voprosy meditsinskoi khimii, 1990, vol: 36(2), 88-91. Scholar google search
