Metabolomics is a novel “omics” branch of science intended for studying a comprehensive set
of low molecular weight substances (metabolites) of various biological objects. Metabolite profiles
represent a molecular phenotype of biological systems and reflect information encoded at the genome
level and realized at the transcriptome and proteome levels. Analysis of human blood metabolic
profile is universal and promising tool for clinical applications because it is a sensitive measure
of both endogenous and exogenous (environmental) factors affected on the patient's organism.
Technical implementation of metabolic profiling of blood and statistic analysis of metabolite profiles
for effective diagnostics and risk assessments of diseases are discussed in this review.
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