The method of extraction and purification of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium has been elaborated. Kinetic characteristics of T-kinase from non-malignant and tumor tissue of women myometrium have been studied. It has been shown, that malignization of myometrium is accompanied by a decrease in affinity of thiamine pyrophosphokinase from tumor to thiamine and by an increase in sensitivity of the enzyme from tumor to thiochrome.
Orishaka O.V., Vovchuk I.L., Petrov S.A. (2014) Extracting and study of biochemical properties of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium. Biomeditsinskaya Khimiya, 60(5), 602-607.
Orishaka O.V. et al. Extracting and study of biochemical properties of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium // Biomeditsinskaya Khimiya. - 2014. - V. 60. -N 5. - P. 602-607.
Orishaka O.V. et al., "Extracting and study of biochemical properties of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium." Biomeditsinskaya Khimiya 60.5 (2014): 602-607.
Orishaka, O. V., Vovchuk, I. L., Petrov, S. A. (2014). Extracting and study of biochemical properties of thiamine pyrophosphokinase from non-malignant and tumor tissue of myometrium. Biomeditsinskaya Khimiya, 60(5), 602-607.
