1. Institute of Biomedical Chemistry, Moscow, Russia; IBMC-EcoBioPharm Company, Moscow, Russia 2. IBMC-EcoBioPharm Company, Moscow, Russia 3. Institute of Biomedical Chemistry, Moscow, Russia
In the review the main approaches to creation of recognition materials capable of competing with biological specific receptors, (polymeric analogs of antibodies or molecularly imprinted polymers, MIP) for the electro analysis of functionally significant proteins such as a myoglobin, troponin T, albumin, human ferritin, calmodulin are considered. The main types of monomers for MIP fabrication, and methods for MIP/protein interactions, such as a surface plasmon resonance (SPR), nanogravimetry with use of the quartz crystal resonator (QCM), spectral and electrochemical methods are discussed. Experimental data on electrochemical registration of a myoglobin using MIP/electrode are presented. For a development of electrochemical sensor systems based on MIPs, o-phenylenediamine (1,2-diaminobenzene was used as a monomer. It was shown that the imprinting factor Imax(MIP)/Imax(NIP), calculated as a myoglobin signal ratio when embedding in MIP to a myoglobin signal when embedding in the polymer received without molecular template (NIP) corresponds 2-4.
Shumyantseva V.V. et al. Molecularly imprinted polymers in electro analysis of proteins // Biomeditsinskaya Khimiya. - 2015. - V. 61. -N 3. - P. 325-331.
Shumyantseva V.V. et al., "Molecularly imprinted polymers in electro analysis of proteins." Biomeditsinskaya Khimiya 61.3 (2015): 325-331.
Shumyantseva, V. V., Bulko, T. V., Baychorov, I. Kh., Archakov, A. I. (2015). Molecularly imprinted polymers in electro analysis of proteins. Biomeditsinskaya Khimiya, 61(3), 325-331.
Verheyen E., Schillemans J.P., van Wijk M., Demeniex M.A., Hennink W.E., van Nostrum C.F. (2011) Biomaterials, 32, 3008-3020. CrossRef Scholar google search
Lieberzeit P.A., Glanznig G., Jenik M., Gazda-Miarecka S., Dickert F.L., Leidl A. (2005) Sensors, 5, 509-518. CrossRef Scholar google search
Malitesta C., Mazzotta E., Picca R.A., Poma A., Chianella I., Piletsky S.A. (2012) Anal Bioanal. Chem., 402, 1827-1846. CrossRef Scholar google search
Zhang X., Peng Y., Bai J., Ning B., Sun S., Hong X., Liu Y., Liu Y., Gao Z. (2014) Sensors and Actuators B, 200, 69-75. CrossRef Scholar google search
Tuyen D., Quan D., Binh N., Nguyen V., Lam T., Huyen L., Nguen L., Viet P., Loc N., Huy T. (2014) J. Mol. Liquids, 198, 307-312. CrossRef Scholar google search
McDonnell B., Hearty S., Leonard P., O'Kennedy R. (2009) Clin Biochem., 42, 549-561. Scholar google search
Karimian N., Vagin M., Hossein M., Zavar A., Chamsaz M., Turner A., Tiwari A. (2013) Biosens. Bioelectron., 50, 492-498. CrossRef Scholar google search
