Determination of strontium content in whole blood and urine by ICP-MS

   
Ulanova T.S.1, Gileva O.V.1, Stenno E.V.1, Veikhman G.A.1 , Nedochitova A.V.1

1. Federal Scientific Center for Medical and Prophylactic Health Risk Management Technologies, Perm, Russia
Section: Experimental Study
DOI: 10.18097/PBMC20156105613      PubMed Id: 26539868
Year: 2015  Volume: 61  Issue: 5  Pages: 613-616
Parameters of strontium determination in the whole blood and urine of children living near ore deposits containing up to 20% strontium sulfate have been determined. The average strontium content in the whole blood of two children groups of 109.52±11.07 mg/L and 131.62±12.95 mg/L, significantly exceeded the level in the comparison group 44.2±4.24 mg/L. The average strontium contents of two groups of children in urine were 1252.3±332.2 mg/L and 1341.5±241.8 mg/L, these values were 4.2 and 4.5 times higher than in the comparison group 296.4±61.5 mg/L. The conditions for blood and urine sample preparation were optimized to reduce measure errors and to determine strontium at the reference concentration level. The accuracy of the results has been confirmed by analysis of the standard samples SeronormTM Whole Blood L1, L2, L3 and SeronormTM Urine.
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Keywords: mass spectrometry, inductively coupled plasma, reaction/collision cell, internal standard, strontium, whole blood, urine
Citation:

Ulanova, T. S., Gileva, O. V., Stenno, E. V., Veikhman, G. A., Nedochitova, A. V. (2015). Determination of strontium content in whole blood and urine by ICP-MS. Biomeditsinskaya Khimiya, 61(5), 613-616.
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