Effect of melaxen on free radical processes intensity and some antioxidant enzymes activity in rats liver and blood serum under type 2 diabetes mellitus

   
Verevkin A.N.1 , Popova T.N.1, Agarkov A.A.1, Semenikhina A.V.1

1. Voronezh State University, Voronezh, Russia
Section: Experimental Study
DOI: 10.18097/PBMC20156105640      PubMed Id: 26539874
Year: 2015  Volume: 61  Issue: 5  Pages: 640-645
The effect of melaxen on free radical processes and activity of superoxide dismutase and catalase in rats with type 2 diabetes mellitus (T2DM) has been investigated. It was established that melaxen administration to diabetic rats caused a decrease of the intensity of free radical processes as evidenced a decrease of the lipid peroxidation primary products content and biochemiluminescence parameters. The activity of the antioxidant enzymes changed towards normal values. These effects were probably induced by the correction of the melatonin level at the result of the melaxen action.
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Keywords: type 2 diabetes mellitus, biochemiluminescence, conjugated dienes, superoxide dismutase, catalase, melaxen
Citation:

Verevkin, A. N., Popova, T. N., Agarkov, A. A., Semenikhina, A. V. (2015). Effect of melaxen on free radical processes intensity and some antioxidant enzymes activity in rats liver and blood serum under type 2 diabetes mellitus. Biomeditsinskaya Khimiya, 61(5), 640-645.
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