Peculiarities of the action of hyaluronidase of different origin to the connective tissue

   
Habriyev R.U.1, Kamayev N.O.2, Danilova T.I.3 , Kakhoyan E.G.4

1. Semashko National Research Institute of Public Health, Moscow, Russia
2. Russian Anti-Doping Agency RUSADA, Moscow, Russia
3. “Biocenter” Ltd, Ivanovo, Ivanovo region, Russia
4. Russian pharmaceutical company “Pharma” Ltd, Moscow, Russia
Section:
DOI: 10.18097/PBMC20166201082      PubMed Id: 26973193
Year: 2016  Volume: 62  Issue: 1  Pages: 82-88
The lecture is devoted to consideration of mechanism of therapeutic action of the enzyme hyaluronidase in hyperplastic connective tissue. Drugs based on hyaluronidase increase bioavailability of other drugs used in adjuvant therapy; they significantly increase effectiveness of treatment, and also provide targeted synthesis of hyaluronic acid, ths regulating the regeneration process of connective tissue.
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Keywords: hyaluronic acid (hyaluronan), connective tissue, extracellular matrix, classification of hyaluronidase, hyaluronidase from the testes of cattle, hyaluronate-lyase from non-pathogenic strain of bacteria of the genus Streptomyces
Citation:

Habriyev, R. U., Kamayev, N. O., Danilova, T. I., Kakhoyan, E. G. (2016). Peculiarities of the action of hyaluronidase of different origin to the connective tissue. Biomeditsinskaya Khimiya, 62(1), 82-88.
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