The role of vascular endothelial growth factor in the regulation of development and functioning of the brain: new target molecules for pharmacotherapy

   
Roslavtceva V.V.1 , Salmina A.B.1, Prokopenko S.V.1, Pozhilenkova E.A.1, Kobanenko I.V.2, Rezvitskaya G.G.2

1. Voyno-Yasenetski Krasnoyarsk State Medical Academy, Krasnoyarsk, Russia
2. Berzon Krasnoyarsk Regional Clinical Hospital N 20, Krasnoyarsk Russia
Section: Review
DOI: 10.18097/PBMC20166202124      PubMed Id: 27143368
Year: 2016  Volume: 62  Issue: 2  Pages: 124-133
Vascular endothelial growth factors (VEGFs) have been shown to participate in atherosclerosis, arteriogenesis, cerebral edema, neuroprotection, neurogenesis, angiogenesis, postischemic brain and vessel repair. Most of these actions involve VEGF-A and the VEGFR-2 receptor. VEGF signaling pathways represent an important potential for treatment of neurological diseases affecting the brain
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Keywords: vascular endothelial growth factors, VEGF, ischemic stroke, brain, neuroprotection, neurogenesis
Citation:

Roslavtceva, V. V., Salmina, A. B., Prokopenko, S. V., Pozhilenkova, E. A., Kobanenko, I. V., Rezvitskaya, G. G. (2016). The role of vascular endothelial growth factor in the regulation of development and functioning of the brain: new target molecules for pharmacotherapy. Biomeditsinskaya Khimiya, 62(2), 124-133.
This paper is also available as the English translation: 10.1134/S1990750816040053
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