Basic carboxypeptidases of blood: significance for coagulology

Timofeev A.V.

doi:10.18097/PBMC20166202141

Basic carboxypeptidases of blood: significance for coagulology

Timofeev A.V.¹

1. Russian Research Institute of Haematology and Transfusiology, Saint Petersburg, Russia

Section: Review

DOI: 10.18097/PBMC20166202141 PubMed Id: 27143370

Year: 2016 Volume: 62 Issue: 2 Pages: 141-149

This review considers the basic metallocarboxypeptidases of human blood and their role in coagulologic disorders. In includes information on the history of the discovery and biological characteristics of potential enzymes-regulators of the fibrinolytic process: carboxypeptidase U and carboxypeptidase N. Certain attention is paid to the biochemical mechanisms and the main modern concepts of the antifibrinolytic effects of these enzymes

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Keywords: basic carboxypeptidases, fibrin, fibrinolysis, plasmin, clot

Citation:

Timofeev, A. V. (2016). Basic carboxypeptidases of blood: significance for coagulology. Biomeditsinskaya Khimiya, 62(2), 141-149.

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