Comparison of the expression profile of surface molecular markers on mesenchymal stromal cell cultures isolated from human endometrium and umbilical cord

   
Lupatov A.Yu.1 , Saryglar R.Yu.1, Chuprynin V.D.2, Pavlovich S.V.2, Yarygin K.N.1

1. Institute of Biomedical Chemistry, Moscow, Russia
2. Research Center of Obstetrics, Gynecology and Perinatology, Moscow, Russia
Section: Short Communication
DOI: 10.18097/PBMC20176301085      PubMed Id: 28251956
Year: 2017  Volume: 63  Issue: 1  Pages: 85-90
Endometrial mesenchymal stromal cells (eMSCs), along with mesenchymal stromal cells (MSCs) isolated from other tissues, are promising for use in regenerative medicine. The benefits of eMSCs include their presence in adults, simplicity of isolation, high proliferative and differentiation capacity. In this study, we have employed the flow cytometry technique to assess expression of 28 molecular markers on the surface of two eMSCs cultures. The culture of MSCs isolated from Wharton's jelly of the umbilical cord (uMSCs) was used as a reference, because uMSCs were studied in details earlier and demonstrated their effectiveness in vivo. Both types of MSCs demonstrated similar expression profiles. They included stem cells surface molecules, cell adhesion molecules and their ligands, some receptor molecules responsible for cell metabolism and proliferation, as well as immunological response molecules.
Download PDF:
Keywords: mesenchymal stromal cells, mesenchymal stem cells, endometrium, molecular markers, umbilical cord
Citation:

Lupatov, A. Yu., Saryglar, R. Yu., Chuprynin, V. D., Pavlovich, S. V., Yarygin, K. N. (2017). Comparison of the expression profile of surface molecular markers on mesenchymal stromal cell cultures isolated from human endometrium and umbilical cord. Biomeditsinskaya khimiya, 63(1), 85-90.
References  
 2020 (vol 66)
 2019 (vol 65)
 2018 (vol 64)
 2017 (vol 63)
 2016 (vol 62)
 2015 (vol 61)
 2014 (vol 60)
 2013 (vol 59)
 2012 (vol 58)
 2011 (vol 57)
 2010 (vol 56)
 2009 (vol 55)
 2008 (vol 54)
 2007 (vol 53)
 2006 (vol 52)
 2005 (vol 51)
 2004 (vol 50)
 2003 (vol 49)