Long-chain fatty acids and short-chain fatty acids in exhaled breath condensate of patients with chronic obstructive pulmonary disease

   
Karavaeva T.M.1 , Maksimenya M.V.1, Tereshkov P.P.1, Gaimolenko I.N.1, Medvedeva T.A.1, Parshina A.A.1

1. Chita State Medical Academy, Chita, Russia
Section: Clinical and Diagnostic Research
DOI: 10.18097/PBMC20216702169      PubMed Id: 33860775
Year: 2021  Volume: 67  Issue: 2  Pages: 169-174
In present study we performed gas-liquid chromatographic analysis of exhaled breath condensate to measure volatile fatty acids (C2 — acetic, C3 — propionic, C4 — butanoic, isoC4 — isobutyric, C5 — valerianic, C6 — caproic, C7 — heptanoic) and fatty acid with a long aliphatic chain (C14:0 — myristic, C15:0 — pentadecanoic, C16:0 — palmitic, C16:1 — palmitooleic, C17:0 — heptadecanoic, C17:1 — heptadecenoic, C18:0 — stearic, C18:1 — oleic, C18:2 — linolenic, C18:3ω3 — α-linolenic, C20:4ω6 — arachidonic) in patients suffering from moderate chronic obstructive pulmonary disease (2nd stage, GOLD). We revealed the increase of the total amount of short chain fatty acids (C2, C3, C4, C5) and polyunsaturated (C18:2, C20:4ω6) fatty acids, meanwhile the level of saturated fatty acids (C16:0, C17:0, C18:0) decreased.
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Keywords: long chain fatty acid, volatile fatty acids, short chain fatty acids, expirate, chronic obstructive pulmonary disease
Citation:

Karavaeva, T. M., Maksimenya, M. V., Tereshkov, P. P., Gaimolenko, I. N., Medvedeva, T. A., Parshina, A. A. (2021). Long-chain fatty acids and short-chain fatty acids in exhaled breath condensate of patients with chronic obstructive pulmonary disease. Biomeditsinskaya Khimiya, 67(2), 169-174.
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