Effect of ethanol on platelet biology

   
Airapetov M.I.1, Eresko S.O.2 , Bychkov E.R.3, Lebedev A.A.3, Shabanov P.D.4

1. Department of Neuropharmacology, Institute of Experimental Medicine, Saint Petersburg, Russia; Department of Pharmacology, St. Petersburg State Pediatric Medical University, Saint Petersburg, Russia
2. Department of Neuropharmacology, Institute of Experimental Medicine, Saint Petersburg, Russia; Research and Training Center of Molecular and Cellular Technologies, Saint Petersburg, Russia
3. Department of Neuropharmacology, Institute of Experimental Medicine, Saint Petersburg, Russia
4. Department of Neuropharmacology, Institute of Experimental Medicine, Saint Petersburg, Russia; Department of Pharmacology, Kirov Military Medical Academy, Saint Petersburg, Russia
Section: Review
DOI: 10.18097/PBMC20226802081      PubMed Id: 35485482
Year: 2022  Volume: 68  Issue: 2  Pages: 81-92
In recent years, interest in the study of platelets, significantly increased due to recent discoveries providing convincing evidence that their functions by are not limited to their participation in the blood coagulation mechanism. Many works are devoted to the study of the functional state of platelets under conditions of acute and chronic alcohol exposure. The results of such studies can be useful for the development of new markers of the degree of alcohol intoxication of the body for the subsequent choice of the method drug correction of disorders caused by acute or chronic alcohol effects. The review summarizes results in vivo and in vitro of studies performed during more than 60 years on the effect of ethanol on the biogenesis, number, morphology and biochemistry of platelets.
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Keywords: platelets, ethanol, alcoholism, blood, thrombopoiesis, thrombocytopenia
Citation:

Airapetov, M. I., Eresko, S. O., Bychkov, E. R., Lebedev, A. A., Shabanov, P. D. (2022). Effect of ethanol on platelet biology. Biomeditsinskaya khimiya, 68(2), 81-92.
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