Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis
Antibodies to thyroid peroxidase (AB-TPO), antibodies to thyroglobulin (AB-TG), and the content of α2-macroglobulin (α2-MG) have been studied in serum samples of patients with autoimmune thyroiditis (AIT). All the patients were divided into 3 groups depending on age: 25–35, 36–50, 51–65 years. We found a significant change in the thyroid panel parameters in AIT, but without significant changes in the average concentration of α2-MG in the age groups of patients. This may be due to the accumulation and retention of complexes of defective forms of α2-MG in the circulation associated with their decreased ability to bind to receptors.
Rahimova R.R., Efendiyev A.M., Shahverdiyeva I.J., Dashdamirova G.S., Kerimova I.A. (2024) Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis. Biomeditsinskaya Khimiya, 70(2), 125-129.
Rahimova R.R. et al. Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis // Biomeditsinskaya Khimiya. - 2024. - V. 70. -N 2. - P. 125-129.
Rahimova R.R. et al., "Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis." Biomeditsinskaya Khimiya 70.2 (2024): 125-129.
Rahimova, R. R., Efendiyev, A. M., Shahverdiyeva, I. J., Dashdamirova, G. S., Kerimova, I. A. (2024). Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis. Biomeditsinskaya Khimiya, 70(2), 125-129.
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