Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1
Nuzhnova A.A.1 , Kostina M.I.1, Blazhenko A.A.2
1. Anichkov Department of Neuropharmacology, Institute of Experimental Medicine, St. Petersburg, Russia; Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russia 2. Anichkov Department of Neuropharmacology, Institute of Experimental Medicine, St. Petersburg, Russia; D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, St. Petersburg, Russia
The effect of a synthetic analog of kisspeptin 1, a peptide involved in the regulation of the hypothalamicpituitary- gonadal (HPG) stress axis, on the cortisol level of Danio rerio fish was investigated. Kisspeptin 1 was administered at doses of 2 μg/kg and 8 μg/kg followed by resting for 1 h and 4 h. We found that kisspeptin at doses of 2 μg/kg and 8 μg/kg increased cortisol levels, with a significant spike in cortisol levels at 1 h post-injection.
Nuzhnova A.A., Kostina M.I., Blazhenko A.A. (2024) Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1. Biomeditsinskaya Khimiya, 70(3), 176-179.
Nuzhnova A.A. et al. Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1 // Biomeditsinskaya Khimiya. - 2024. - V. 70. -N 3. - P. 176-179.
Nuzhnova A.A. et al., "Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1." Biomeditsinskaya Khimiya 70.3 (2024): 176-179.
Nuzhnova, A. A., Kostina, M. I., Blazhenko, A. A. (2024). Dynamics in cortisol levels in Danio rerio fish under the influence of a synthetic analog of kisspeptin 1. Biomeditsinskaya Khimiya, 70(3), 176-179.
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