VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Mitochondrial monoamine oxidase in progressive Duchenne muscular dystrophy

   
Badalian L.O., Amanova Z.N., Temin P.A., Grinio L.P., Severina I.S.
PubMed Id: 3984276
Year: 1985  Volume: 31  Issue: 1  Pages: 68-71
In children with progressive Duchenne muscular dystrophy distinct impairment in activity, of mitochondrial monoamine oxidase from skeletal muscles correlated with the step of myodystrophic process. The decrease in activity of monoamine oxidase in mitochondria of skeletal muscles, occurred with simultaneous increase in intensity of amines deamination in a medium surrounding the organelles, might de due to "leakage" of the enzyme as a result of deterioration of mitochondrial membranes permeability developed in the disease.
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Badalian L.O., Amanova Z.N., Temin P.A., Grinio L.P., Severina I.S. (1985) Voprosy meditsinskoi khimii, 31(1), 68-71.
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