VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Peroxidation of blood serum lipids in rabbits with various thyroid functions

   
Marzoev A.I., Klebanov G.I., Sherstnev M.P., Andriushchenko A.P.
PubMed Id: 4002651
Year: 1985  Volume: 31  Issue: 2  Pages: 14-17
Chemiluminescent properties of blood serum from rabbits with hypo-, normo- and hyperthyroidism were investigated. The ferrum-induced chemiluminescence of the serum was shown to be decreased both in hypo- and in hyperthyroidism as compared with the normal state. The oxidative capacity of the main substrate of the peroxidation in blood serum--apo-B containing lipoproteins--did not markedly differ in various states of thyroid gland. The efficiency of branched free radical chains was dissimilar; these data suggest that the content of lipid-soluble antioxidants was increased in the lipoproteins in hypo- and decreased in hyperthyroidism. Measuring of the chemiluminescence quenching in the standard chemiluminescent system indicated that the content of water-soluble antioxidants was increased in blood of animals both with hypo- and hyperthyroidism. However, a higher content of water-soluble antioxidants was noted in blood of rabbits with hypothyroidism as compared with the animals with hyperthyroidism.
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Marzoev A.I., Klebanov G.I., Sherstnev M.P., Andriushchenko A.P. (1985) Voprosy meditsinskoi khimii, 31(2), 14-17.
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