VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Mechanism of action of sodium oxybutyrate in experimental myocardial infarction

   
Bashirova N.S., Usmankhodzhaeva A.I., Paleologu A.K.
PubMed Id: 4024532
Year: 1985  Volume: 31  Issue: 3  Pages: 61-64
Effect of sodium hydroxybutyrate on lipid metabolism was studied in experimental infarction of rabbit myocardium. Administration of 80 mg of sodium hydroxybutyrate per kg of body mass caused a decrease of free fatty acids content in the infarction zone, in surrounding zones and in blood. Treatment of the experimental animals with sodium hydroxybutyrate normalized distinctly the phospholipid composition of the ischemized myocardium. Content of phosphatidyl choline, phosphatidyl ethanolamine and cardiolipine was increased in the infarction zone and in surrounding zones of myocardium. Concentration of lysolecithines was decreased in the both zone studied. In the animals treated with sodium hydroxy butyrate after the infarction output of myocardial creatine kinase into circulation was decreased.
Download PDF:  
Citation:

Bashirova, N. S., Usmankhodzhaeva, A. I., Paleologu, A. K. (1985). Mechanism of action of sodium oxybutyrate in experimental myocardial infarction. Voprosy Meditsinskoi Khimii, 31(3), 61-64.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)
◄        ►