VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Comparison of the effect of homologous and heterologous albumin on the activity of lipoprotein lipase and liver triglyceride lipase in rabbit plasma

   
Klimov A.N., Serrano D.S., Nikul'cheva N.G., Soliternova I.B.
PubMed Id: 4024538
Year: 1985  Volume: 31  Issue: 3  Pages: 93-99
Changes in the activity of blood plasma lipoprotein lipase (EC 3.1.1.34, LPL and hepatic triacylglycerol lipase EC 3.1.1.3, H-TGL) were studied in rabbits injected intravenously by homologous and heterologous albumins (bovine, fraction Y, Sigma, BSA) alone and in combination with heparin. Rabbit albumin enhanced the effect of heparin on the LPL activity, while heterologous protein, to the contrary, diminished it. The in vitro experiments showed that BSA caused a more distinct effect on the LPL activity as compared with that of rabbit albumin. The activity of H-TGL was not significantly altered under the influence of both proteins.
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Klimov A.N., Serrano D.S., Nikul'cheva N.G., Soliternova I.B. (1985) Voprosy meditsinskoi khimii, 31(3), 93-99.
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