VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Effect of cytoplasmic proliferation stimulating factors and partial hepatectomy on DNA synthesis in the liver of rats subjected to prolonged carbon tetrachloride exposure

   
Abakumova O.Yu., Kotaev A.Yu., Karagiulian S.R., Gal'perin E.I., Orekhovich V.N.
PubMed Id: 2418589
Year: 1985  Volume: 31  Issue: 5  Pages: 95-97
Content of RNA was increased, synthesis of nuclear and mitochondrial DNA was induced in liver tissue of rats, which were poisoned with CCl4, within 6 weeks, after intraperitoneal administration of the preparation obtained from regenerating rat liver tissue and containing thermostable factors stimulating proliferation, as well as the low molecular substances of the cell pool. The most pronounced stimulating effect was observed if the administration of the preparation occurred simultaneously with 30% hepatectomy.
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Abakumova, O. Yu., Kotaev, A. Yu., Karagiulian, S. R., Gal'perin, E. I., Orekhovich, V. N. (1985). Effect of cytoplasmic proliferation stimulating factors and partial hepatectomy on DNA synthesis in the liver of rats subjected to prolonged carbon tetrachloride exposure. Voprosy meditsinskoi khimii, 31(5), 95-97.
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