VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Vitamin A: effect on phagocytosis and neutrophil bactericidal systems under normal conditions and in various pathological states

   
Davydova T.V., Pletsityĭ K.D., Vasipa S.B.
PubMed Id: 4090390
Year: 1985  Volume: 31  Issue: 6  Pages: 70-74
Effect of vitamin A on phagocytic activity and the state of bactericide system involving myeloperoxidase and cationic proteins was studied in neutrophils from peripheric blood of volunteers and of the patients with chronic pneumonia and lung cancer. Vitamin A was administered per os within 1 week at a daily dose of 500,000 IU. In healthy persons vitamin A, not affecting the ability of neutrophils to capture and lyse microbes, activated myeloperoxidase and increased the cationic proteins content. Under conditions of lung cancer the vitamin did not alter any patterns of phagocytosis studied. Vitamin A did not affect the capture and lysis of microbes in chronic pneumonia but increased distinctly the myeloperoxidase activity in neutrophils, impaired during the disease, and normalized partially the content of cationic proteins.
Download PDF:  
Citation:

Davydova, T. V., Pletsityĭ, K. D., Vasipa, S. B. (1985). Vitamin A: effect on phagocytosis and neutrophil bactericidal systems under normal conditions and in various pathological states. Voprosy Meditsinskoi Khimii, 31(6), 70-74.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)
◄        ►