VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Primary structure and species specificity of immunopoietins

   
Chipens G.I., Zarin'sh P.P., Osis L.P., Antsans Yu.E.
PubMed Id: 3705517
Year: 1986  Volume: 32  Issue: 2  Pages: 59-64
A model involving quasicyclization of protein molecules following the stepwise reactions of limited proteolysis was developed. On the basis of the model new active sites were detected in immunoglobulins of various species as well as chemical synthesis of the sites was carried out. The new group of the substances was designated as immunopoietins. The primary structure of various species immunoglobulins was analyzed and evolutional stability of the immunopoietin structure was shown.
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Chipens, G. I., Zarin'sh, P. P., Osis, L. P., Antsans, Yu. E. (1986). Primary structure and species specificity of immunopoietins. Voprosy Meditsinskoi Khimii, 32(2), 59-64.
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