VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Effect of the synthetic tetradecapeptide corresponding to the amino acid sequence of human somatotropin 31-44 on rat blood and liver lipids

   
Ryzhenkov V.E., Pankov I.A., Chistiakova A.M., Keda I.M., Serrano D.S.
PubMed Id: 3727464
Year: 1986  Volume: 32  Issue: 3  Pages: 108-111
Although synthetic tetradecapeptide, involving the 31-44 amino acid sequence of human growth hormone, exhibited a distinct lipolytic effect, content of triglycerides was not increased in rat blood and liver tissue during chronic experiments. At the same time, the level of atherogenic lipoproteins as well as activities of postheparin lipase and liver triglyceride lipase were also unaltered. The data obtained suggest that the tetradecapeptide studied stimulated simultaneously both lipolysis and oxidation of free fatty acids.
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Ryzhenkov, V. E., Pankov, I. A., Chistiakova, A. M., Keda, I. M., Serrano, D. S. (1986). Effect of the synthetic tetradecapeptide corresponding to the amino acid sequence of human somatotropin 31-44 on rat blood and liver lipids. Voprosy Meditsinskoi Khimii, 32(3), 108-111.
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