Influence of retinoid C17-diester retinyldimedone and L-tocopherylretinoate on the growth of transplanted tumors was investigated in F1 (C57Bl/6 X CBA) strain of mice. The retinoids studied proved to be less toxic than retinoic acid. Both retinoid C17-diester and L-tocopherylretinoate reduced growth of cervical cancer, while retinyldimedone inhibited growth of Lewis carcinoma (lung tumor) and of stomach carcinoma.