VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Thrombin neutralization by antithrombin III depending upon the intensity of thrombin-formation in experimental and clinical surgical interventions

   
Pastorova V.E., Tabakina T.E., Ivanov A.Yu.
PubMed Id: 3776113
Year: 1986  Volume: 32  Issue: 5  Pages: 28-32
Low rate of thrombinogenesis, its gradual and prolonged development in animal circulation after small-scale surgical operations was accompanied by a compensatory increase in the activity of antithrombin III. After surgical operations of lung in children thrombinoformation at the high rate led to distinct short-term consumption and to decrease in activity of the inhibitor during the operation period and within 2-3 days after the operation simultaneously with activation of enzymatic and nonenzymatic fibrinolysis. At the same time, any postoperational thrombotic complications were not observed in the children.
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Pastorova, V. E., Tabakina, T. E., Ivanov, A. Yu. (1986). Thrombin neutralization by antithrombin III depending upon the intensity of thrombin-formation in experimental and clinical surgical interventions. Voprosy Meditsinskoi Khimii, 32(5), 28-32.
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