VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The role of lipid peroxidation in the process of thermal inactivation of tissue thromboplastin

   
Svintenok G.Yu., Zubairov D.M.
PubMed Id: 3811295
Year: 1986  Volume: 32  Issue: 6  Pages: 80-81
Thermic inactivation of tissue thromboplastin in air led to an increase in concentration of malonic dialdehyde and to decrease in activity of thromboplastin. Thromboplastin, treated with ionol, exhibited a less distinct loss of the hemocoagulation activity on heating. Inactivation of the tissue thromboplastin in air during thermic treatment involved at least three steps: thermic denaturation of apoprotein III, lipid peroxidation of the lipid component, observed in the experiment, oxidation of apoprotein III and destruction of its lipid moiety.
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Svintenok, G. Yu., Zubairov, D. M. (1986). The role of lipid peroxidation in the process of thermal inactivation of tissue thromboplastin. Voprosy Meditsinskoi Khimii, 32(6), 80-81.
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