VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Purification of radioactive sex hormones as receptor ligands

   
Degtiar' V.G., Kushlinskii N.E., Khotchenkova N.V.
PubMed Id: 3604146
Year: 1987  Volume: 33  Issue: 2  Pages: 71-73
A system (mobile phase) containing benzene:acetone:absolute ethanol 9:1:0.5, respectively, is described for thin-layer chromatography on Silufol plates of ligand receptors of sex steroid hormones 3H-5 alpha-androstan-3 beta, 17 beta-diol, 3H-estradiol-17 beta, 3H-5 alpha-dihydrotestosterone, 3H-methyltrienolone (R 1881), 3H-OPG 2058 and 3H-progesterone. A purity of commercially available 3H-steroids was decreased in storage, therefore they should be purified before use. The system described enabled to produce the 3H-steroids studied of high purity.
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Degtiar', V. G., Kushlinskii, N. E., Khotchenkova, N. V. (1987). Purification of radioactive sex hormones as receptor ligands. Voprosy meditsinskoi khimii, 33(2), 71-73.
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