VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Lysosomotropic agents as regulators of the activity of lysosomal hydrolases

   
Bulychev A.G., Assinovskaia O.A., Semenova E.G.
PubMed Id: 3686895
Year: 1987  Volume: 33  Issue: 5  Pages: 20-24
Activities of lysosomal enzymes acid phosphatase, N-acetyl-beta-D-glucosaminidase, beta-galactosidase, acid lipase and cathepsins B and D were studied after accumulation of neutral red, acridine orange chloroquine and daunorubicin in lysosomes of fibroblasts of the LSM substrain. All the drugs studied proved to be inhibitors of these enzymes except of daunorubicin, which stimulated acid lipase activity. Lysosomotropic drugs are considered as possible regulators of the activity of lysosomes.
Download PDF:
Citation:

Bulychev, A. G., Assinovskaia, O. A., Semenova, E. G. (1987). Lysosomotropic agents as regulators of the activity of lysosomal hydrolases. Voprosy meditsinskoi khimii, 33(5), 20-24.
References
 2002 (vol 48)
 2001 (vol 47)
 2000 (vol 46)
 1999 (vol 45)
 1998 (vol 44)
 1997 (vol 43)
 1996 (vol 42)
 1995 (vol 41)
 1994 (vol 40)
 1993 (vol 39)
 1992 (vol 38)
 1991 (vol 37)
 1990 (vol 36)
 1989 (vol 35)
 1988 (vol 34)
 1987 (vol 33)
 1986 (vol 32)
 1985 (vol 31)