VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Na,K-ATPase activity of erythrocyte ghosts of mammals in the presence of alamethicin and p-nitrophenylphosphate

   
Sokol'nikov A.A., Kodentsova V.M., Gulidova G.P., Mironova G.D.
PubMed Id: 2840771
Year: 1988  Volume: 34  Issue: 2  Pages: 53-56
After preincubation of erythrocyte ghosts isolated from Sprague-Dawley rats activity of Na, K-ATPase was more successfully manifested, being elevated about 2.5-fold, while the ratio Mg-ATPase/Na, K-ATPase was decreased 3-fold. Optimal ratio of alamethicin/protein was equal to 0.3. The similar results were obtained if p-nitrophenyl phosphate, easily penetrating through the erythrocyte membrane, was used as an exogenous substrate.
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Sokol'nikov, A. A., Kodentsova, V. M., Gulidova, G. P., Mironova, G. D. (1988). Na,K-ATPase activity of erythrocyte ghosts of mammals in the presence of alamethicin and p-nitrophenylphosphate. Voprosy meditsinskoi khimii, 34(2), 53-56.
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