VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Hypoinsulinemia and bioenergetic processes in the rat cerebral cortex

   
Cheshchevik A.B.
PubMed Id: 3047969
Year: 1988  Volume: 34  Issue: 3  Pages: 16-18
Increase in activity of lactate dehydrogenase, of its isoenzymes LDH1, LDH2 and LDH3 as well as in content of lactic acid with simultaneous decrease in the pyruvic acid content were found in brain hemispheres of rats with alloxan diabetes. A decrease in the rate of energy reactions in rat brain hemispheres, caused by impairment of glucose oxidation in the Krebs cycle, proved to be the specific property of metabolic alterations in these cells under conditions of hypoinsulinemia.
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Cheshchevik, A. B. (1988). Hypoinsulinemia and bioenergetic processes in the rat cerebral cortex. Voprosy Meditsinskoi Khimii, 34(3), 16-18.
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