VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

The state of membrane structures of heart cells during ischemia

   
Dagis A.I., Toleykis A.I., Prashkyavichius A.K.
PubMed Id: 2851212
Year: 1988  Volume: 34  Issue: 5  Pages: 80-83
Under conditions of perfusion of isolated rabbit heart in aerobic medium and, especially, during ischemia, cytochrome c was liberated from heart cells into perfusate, thus indicating that integrity of mitochondrial outer membrane and of cell membrane was impaired. In situ developed deficiency of cytochrome c was distinctly less as compared with isolated mitochondria (50%, 3 hrs perfusion in ischemia), which appears to occur in response to ultrastructural impairments of mitochondria arising during their isolation and to other reasons.
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Dagis, A. I., Toleykis, A. I., Prashkyavichius, A. K. (1988). The state of membrane structures of heart cells during ischemia. Voprosy Meditsinskoi Khimii, 34(5), 80-83.
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